WSC 2023 | Advancing stroke care: insights from the World Stroke Congress

Sean I. Savitz, MD, Institute for Stroke and Cerebrovascular Diseases at UTHealth Houston, Houston, TX, shares insights from the World Stroke Congress 2023, unveiling promising findings from several clinical trials in stroke care. Notably, the TENSION study (NCT03094715) demonstrates the potential benefits of endovascular thrombectomy for patients with large core ischemic strokes identified via non-contrast CT. Additionally, a trial investigating the neuroprotective effects of nerinetide, a peptide that perturbs NMDA receptor-PSD-95 protein interactions, indicates improved patient outcomes when administered within 60 minutes of stroke onset (FRONTIER; NCT02315443). Another intriguing highlight revolves around the ANNEXA-I study (NCT03661528), demonstrating the strong efficacy of andexanet alfa in the treatment of patients with intracranial hemorrhage related to factor Xa inhibitor administration. These innovations promise a new frontier in stroke care. This interview took place at the World Stroke Congress (WSC) 2023 in Toronto, Canada.

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