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EAN 2023 | Factors influencing genetic testing for hemiplegic migraine

Irene de Boer, MD, Leiden University Medical Center, Leiden, Netherlands, discusses the various factors that can increase the likelihood of finding a mutation through genetic testing in hemiplegic migraine patients. Patients who experience their first attack at a young age, particularly those below 10 years old, have an increased chance of having a pathogenic mutation. Additionally, if multiple family members are affected or if patients have mental retardation and their attacks are triggered by mild head trauma, there is a higher probability of finding a mutation. Furthermore, if an MRI scan during an attack reveals swelling in one hemisphere, it indicates the presence of a mutation rather than a case of mild hemiplegic migraine. These factors can be valuable when considering genetic testing for patients with hemiplegic migraine. This interview took place at the European Academy of Neurology (EAN) 2023 Congress in Budapest, Hungary.

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