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AHS 2023 | Implications of differences between left- and right-sided migraine

Adam Sprouse Blum, MD, University of Vermont, Burlington, VT, discusses the implications of a recent study that suggested that migraine with left-side headache has more frequent and severe attacks than migraine with right-side headache. Left- and right-sided migraines may respond differently to treatment, which highlights the importance of recording the location of headaches in clinical trials for acute treatments. It may also be essential to ensure that participant groups in clinical trials for migraine prevention do not favor one headache laterality as this could create a confounding variable in the outcomes due to the different frequencies of left- and right-sided migraines. However, there are limitations to this study as the results are yet to be validated by larger datasets. This interview took place at the American Headache Society 2023 meeting in Austin, TX.

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