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AES 2023 | Considerations for the management of epilepsy in older adults

Ifrah Zawar, MD, University of Virginia School of Medicine, Charlottesville, VA, comments on key considerations for the management of epilepsy in older adults. The higher comorbidity rate and increased mortality risk in older adults with epilepsy have implications when considering optimal treatment strategy. Critical considerations in this population include the potential contributory role of medications to adverse outcomes. A study involving individuals with epilepsy and Alzheimer’s disease revealed higher mortality rates among those using older generation antiseizure medications (ASMs) compared to newer ones. The recommendation is to prioritize newer medications with fewer side effects, especially concerning cardiac implications in the elderly. Additionally, as certain medications may impact bone health, ensuring vitamin D and calcium supplementation for those on medications causing bone loss is essential. Careful selection of medications and vigilant monitoring of side effects are paramount in managing epilepsy in older populations. This interview took place during the American Epilepsy Society (AES) 2023 Annual Meeting congress in Orlando, FL.

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