Addiction is a chronic disorder characterized by the long-term propensity of addicted individuals to relapse. Therefore, prevention of relapse is a key target for enhancing addiction treatment. Amy Milton, PhD, University of Cambridge, Cambridge, UK, discusses one promising form of addiction treatment based on the disruption of memory reconsolidation. If cue drug memories could be disrupted, it should be possible to reduce the long-term risk of relapse. This interview was recorded during an online conference call with The Video Journal of Neurology (VJNeurology).