ESOC 2023 | Feasibility trial of intensive vs. standard BP control after endovascular treatment

Aristeidis Katsanos, MD, McMaster University, Hamilton, Ontario, Canada, discusses a pilot phase randomized trial assessing intensive versus standard blood pressure (BP) lowering after successful endovascular thrombectomy (EVT) for large vessel occlusion stroke. The small-scale trial was predominantly conducted to determine if it would be feasible to undertake a full-scale RCT. In total, 30 patients with persistently elevated BP were randomized within one hour following EVT. It was noted that the natural course of BP normalization led to difficulties maintaining BP within assigned targets in both the standard and intensive group. Only 75% and 48% of 48-hour BP readings were within the goal ranges in the intensive and standard arms, respectively. Transcranial doppler ultrasound after EVT was also undertaken to determine if there was a difference in the peak systolic velocities between the control and intensive arms, however no evidence of this was found. This interview took place during the European Stroke Organisation Conference (ESOC) in Munich, Germany.

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