Kartik Bhatia, MBBS, PhD, Sydney Children’s Hospital Network, University of Sydney, Westmead, Australia, shares the findings of a new case-control study assessing the value of endovascular thrombectomy (EVT) compared to conservative management in pediatric large vessel occlusion stroke. The occurrence of ischemic stroke in children is rare. While there is a growing tendency to utilize reperfusion therapy in pediatric cases, the lack of clinical trial evidence and up-to-date guidelines has led to uncertainty regarding the optimal approach. In this study, Dr Bhatia and his team pooled stroke registry data from all patients age under 18 who received EVT or medical management in five hospitals over a 10-year period. Consensus matching of cases and controls was undertaken, accounting for age, sex, occlusion site, and hemisphere. The pediatric mRS results from 26 EVT cases and their matched controls showed that EVT use resulted in significantly better clinical outcomes at 3 months, compared to medical management (OR 3.76). Dr Bhatia notes the importance of developing new guidelines based on this comparative evidence. This interview took place during the International Stroke Conference (ISC) 2023 in Dallas, TX.
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