ECTRIMS 2023 | Elevated intracranial pressure in MOGAD patients with bilateral optic neuritis

Torge Rempe, MD, PhD, University of Florida College of Medicine, Gainesville, FL, discusses findings concerning patients with myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) presenting with bilateral optic neuritis. Within their cohort, six patients displayed increased intracranial pressure, with pressure values reaching up to 44. Notably, for all these patients, this was their initial disease episode. The study underscores the potential risk of misdiagnosis, such as confusing this presentation with idiopathic intracranial hypertension. One patient, for instance, received a shunt placement. Prof. Rempe advocates for the consideration of immunotherapy as a fitting intervention, given the immune-related nature of the condition. Healthcare professionals should be vigilant in their diagnostic approach to such presentations. This interview took place at the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Congress 2023 in Milan, Italy.

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