EAN 2026 | What are the key changes introduced in the 2024 revision of the McDonald diagnostic criteria for MS?

Mar Tintoré, MD, PhD, Vall d’Hebron University Hospital, Barcelona, Spain, discusses the 2024 revision of the McDonald diagnostic criteria for multiple sclerosis (MS), highlighting the shift from a clinical to a biological diagnosis. Dr Tintoré notes that the new criteria provide a “box of tools” to increase sensitivity and specificity, including optic nerve examination and central vein sign, and that these tools can be adapted to different clinical scenarios and resource availability. This interview took place at the 12th Congress of the European Academy of Neurology (EAN) in Geneva, Switzerland.

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