Andrew Demchuk, MD, FRCPC, Hotchkiss Brain Institute, University of Calgary, Calgary, Canada, discusses the potential of biomarkers to identify patients with true ischemia. In practice, MRI is a limited resource and is not always available immediately. Therefore, the use of a less expensive method, like biomarkers, would be beneficial. This interview took place during the Virtual World Congress on Controversies in Neurology (CONy) 2020.