Carmen Barba, MD, PhD, Meyer Children’s Hospital, University of Florence, Florence, Italy, talks on a recent systematic review and meta-analysis that investigated seizure outcomes after temporal lobe epilepsy (TLE) surgery in adults and children. The study aimed to identify determinants of seizure outcome after surgery. Follow-up duration, type of surgery, histopathology, and neuroimaging were all assessed. Over 30,000 patients were included in the study, which showed a higher proportion of seizure freedom (Engel I/ILAE 1 and Engel IA/ILAE 1A) after TLE surgery in children compared to adults. Histopathology significantly influenced outcomes in adults, while surgery type significantly influenced outcome in children. Prof. Barba shares her thoughts on why the outcomes and determinants differ between children and adults. This interview took place at the American Epilepsy Society (AES) Annual Meeting 2022 in Nashville, TN.
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