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CONy 2023 | Benefits & risks of cholesterol-lowering strategies in people with non-atherosclerotic stroke

Christine Kremer, MD, Skåne University Hospital, Lund University, Malmö, Sweden, discusses aggressive cholesterol-lowering to improve outcomes in people with non-atherosclerotic stroke. There is clear evidence that aggressive cholesterol-lowering improves outcomes in patients with coronary artery disease and those with stroke who have evidence of atherosclerosis. However, there are some concerns about the increased risk of cerebral hemorrhage due to statins. And there is less certainty regarding the benefit of aggressive cholesterol reduction in people with cardioembolic stroke, small vessel disease, and lacunar stroke. Additionally, the benefit of cholesterol-lowering strategies has not been shown in older women, as most studies have studied the effects in men under the age of 75. This is important because older women have a higher tendency to have cardio-embolic strokes rather than atherosclerotic ones. This interview took place at the 17th World Congress on Controversies in Neurology (CONy) in Dubrovnik, Croatia.

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