ESOC 2025 | Differentiating AIS from ICH in the ambulance to guide blood pressure management

Yes, because last year we published an article, it’s called INTERACT-4 trial on the New England Journal of Medicine, and we proved that the super early blood pressure lowering is very effective for ICH patients. And if you can lower the blood pressure in patients with intracerebral hemorrhage, even 20 minutes pre-hospital, before hospital admission, you can reduce like 25% of death and morbidity. So it’s quite useful information for us. So from this, however, because we cannot differentiate ICH from AIS in a normal ambulance, so actually because INTERACT-4 also showed another unexpected trial result that for acute ischemic stroke patients, actually early blood pressure lowering will bring harm to the patient. So if we cannot identify ICH from AIS patients in the ambulance, actually we cannot give a very effective blood pressure lowering treatment to the patient. So it’s quite critical to identify ICH patients from AIS patients in a normal ambulance. So currently, actually, we have mobile stroke units. If we use this CT car, CT ambulance, the problem can be resolved. However, because this is very expensive, and actually, it’s not unusual in the world. Only very few places can run this mobile stroke unit. So actually, the new technology for differentiating ICH patients from AIS patients is quite critical. So yeah, it deserves us to put more efforts on this kind of studies.

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