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WSC 2022 | Biomarkers in small vessel disease

Hsin-Hsi Tsai, MD, National Taiwan University Hospital, Taipei, Taiwan, discusses both traditional and newer biomarkers of small vessel disease. There are numerous valuable biomarkers in small vessel disease, but the main focus is on neuroimaging biomarkers. The well-established and widely implemented biomarkers include cerebral microbleeds, white matter hyperintensities, and enlarged perivascular spaces. The newer biomarkers of small vessel disease include cortical microinfarcts detected through high resolution T1-FLAIR imaging, as well as vascular reactivity and blood-brain barrier leakage parameters. Fluid biomarkers of small vessel disease also appear promising, however more research is needed to further our understanding of them. This interview took place at the World Stroke Congress 2022 in Singapore.

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