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ECTRIMS 2023 | Combined physical and cognitive treatment for cognitive impairment in MS

Ulrik Dalgas, PhD, Aarhus University, Aarhus, Denmark, discusses the results of the CogEx study, which aimed to evaluate the effects of combining physical exercise with cognitive rehabilitation on cognitive impairment in individuals with progressive multiple sclerosis (MS). The study recruited over 300 MS patients with cognitive impairment and found that both the exercise and cognitive rehabilitation groups, as well as the sham groups, showed improvement in cognitive performance. This finding suggests that engaging in any form of activity may be beneficial for cognitive function in individuals with cognitive impairments and progressive MS. However, the study also highlights that exercise alone may not be the most effective treatment for cognitive impairment in this population. Further research is needed to fully understand and interpret these results. This interview took place at the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Congress 2023 in Milan, Italy.

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I have received research support, travel grants, or teaching honoraria from Biogen Idec, Merck Serono, Novartis, Bayer Schering, and Sanofi Aventis as well as honoraria from serving on scientific advisory boards of Biogen Idec and Genzyme.