ISC 2024 | Brain20 device able to predict recovery in patients with ischemic stroke undergoing EVT

Alicia Martinez-Piñeiro, MD, PhD, Time is Brain & University Hospital Germans Trias I Pujol, Barcelona, Spain, discusses her work towards the clinical validation of a portable medical device (Brain20) capable of predicting functional recovery in patients with acute ischemic stroke undergoing endovascular thrombectomy (EVT). Dr Martinez-Piñeiro likens Brain20 to an ECG for stroke, as it can monitor brain viability in real time. The device measures N20 somatosensory potentials, which reflect the electrical activity of brain different areas and correlate with cortical cerebral perfusion. Observational studies have shown that presence of the N20 component in somatosensory evoked potentials predicted functional independence (mRS 0-2) with a sensitivity of 93% prior to EVT and 100% after EVT, outperforming prehospital or in-hospital variables, including advanced imaging. Additionally, it added significant value when used in additional to current advanced imaging sequences. By enabling fast and non-invasive recording of brain viability before and during EVT, Brain20 has the potential to improve patient selection and predict recovery. This interview took place during the International Stroke Conference 2024 in Phoenix, AZ.

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