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WSC 2022 | Sex-differences in patients with OAC-ICH

Hanne Christensen, MD, PhD, MSci, University of Copenhagen, Copenhagen, Denmark, discusses some of the differences in risk factors, treatment utilization, and outcomes between men and women admitted with oral anticoagulant (OAC)-related intracerebral hemorrhage (ICH). The data comes from a study on 401 patients, 226 men and 175 women. While women in the study tended to be older than men, the National Institute of Health Stroke Scale (NIHSS) scores and hematoma volumes across the two groups were not statistically different. The treatment positivity was lower in women than in men, with women having a lower probability of receiving interventions and a higher chance of receiving do-not-resuscitate (DNR) orders within a week. Prof. Christensen considers the reason for this to be an implicit bias that women are typically viewed as weaker or more fragile. While this study supports the presence of sex differences in care, outcomes in men and women were comparable. This interview took place at the World Stroke Congress 2022 in Singapore.

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Hanne Christensen is national lead for the ANNEXA-i trial and has received speaker’s honoraria from BMS and Bayer.