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AAN 2023 | The relationship between oral, mandibular, and facial disorders and migraine

Marcela Romero-Reyes, DDS, PhD, University of Maryland, Baltimore (UMB), Baltimore, MD, discusses the comorbidities and associations between oral, mandibular, and facial disorders and migraine. Patients with temporomandibular disorders (TMD) often present with migraine, which can be more severe and frequent when TMD is present. TMD-related peripheral inputs can activate the trigeminal system, exacerbating migraine symptoms. The role of calcitonin gene-related peptide (CGRP) is a key molecule involved in both TMD and migraines, suggesting a potential for future monotherapy options. An association between chronic periodontitis and chronic migraines is currently being explored, indicating a possible systemic inflammation connection. Further research is needed to understand these relationships fully. This interview took place at the American Academy of Neurology Annual Meeting 2023 in Boston, MA.

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