WSC 2025 | Novel strategies being explored for the secondary prevention of non-cardioembolic stroke
Valeria Caso, MD, PhD, FESO, Santa Maria Della Misericordia Hospital, University of Perugia, Perugia, Italy, discusses new strategies for the secondary prevention of non-cardioembolic stroke, including the potential of Factor XIa inhibitors to reduce stroke recurrence without increasing the risk of bleeding. Dr Caso highlights the need for improved prevention, as one in five stroke patients will experience another stroke within five years. This interview took place at the 17th World Stroke Congress (WSC) in Barcelona, Spain.
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Transcript
There are new strategies regarding non-cardioembolic stroke, for example now Factor XI. We are really eagerly waiting for the results because it seems that it works especially in non-cardioembolic stroke, atherosclerotic stroke, lacunar stroke. So we will see if we add on top of what we have now, aspirin and DAPT, adding Factor XI, which does not increase the risk of bleeding, will you reduce the stroke recurrence...
There are new strategies regarding non-cardioembolic stroke, for example now Factor XI. We are really eagerly waiting for the results because it seems that it works especially in non-cardioembolic stroke, atherosclerotic stroke, lacunar stroke. So we will see if we add on top of what we have now, aspirin and DAPT, adding Factor XI, which does not increase the risk of bleeding, will you reduce the stroke recurrence. And for us, we know that one in five will have another stroke in five years. So we need to do better because if you tell an oncological patient that one in four or five will have a recurrence, there will be a lot of engagement to change this. This is the same engagement we have to create for our stroke patients.
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