EAN 2025 | A clinical case of a transgender woman with MS receiving gender-affirming care
Marcello Moccia, MD, PhD, University of Naples Federico II, Naples, Italy, highlights the need for more research on the intersection of gender-affirming care and multiple sclerosis (MS) due to the interplay between hormones and MS risk. He presents a case where gender-affirming care was successfully given while managing disease-related issues. This interview took place at the 11th Congress of the European Academy of Neurology (EAN 2025) in Helsinki, Finland.
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Transcript
It’s just a single case report, but unfortunately the medical literature has very few reports of transgender people with MS. I think this is quite a relevant issue because there is a strong interplay between hormones and the risk of MS and the risk of worsening of MS. But in the meantime, I believe that we need to support in any possible way gender-affirming care in MS and that means that we need to get a bit more knowledge...
It’s just a single case report, but unfortunately the medical literature has very few reports of transgender people with MS. I think this is quite a relevant issue because there is a strong interplay between hormones and the risk of MS and the risk of worsening of MS. But in the meantime, I believe that we need to support in any possible way gender-affirming care in MS and that means that we need to get a bit more knowledge. We described actually a case that was quite successful where we were able to provide gender-affirming care in a successful way while fully controlling disease-related issues. But unfortunately again there is very little literature.
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