WSC 2026 | EVATRISP collaboration: FRET score to predict failed thrombectomy in stroke
Ronen Leker, MD, Hadassah-Hebrew University Medical Center, Jerusalem, Israel, discusses a study from the EVATRISP collaboration, in which academic centers across Europe and Israel share data on patients treated with endovascular thrombectomy (EVT). Prof. Leker explains that the study identified predictors of failed thrombectomy, or futile recanalization, where patients do poorly despite complete recanalization. These were used to develop the FRET score, which uses variables easily obtained on admission to predict which patients are unlikely to benefit from EVT. This interview took place at the 18th World Stroke Congress (WSC) in Seoul, Korea.
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Transcript
So we had a large study based on the EVATRISP collaboration, which is a collaboration of 28 medical centers across Europe and Israel, academic centers that contribute data on patients with EVT towards a shared database. And we looked specifically at that database to see if we can find predictors for failed thrombectomy. Failed thrombectomy is basically when you perform a thrombectomy on a stroke patient, you remove the clot, and still the patient doesn’t do well, despite the fact that you have achieved complete recanalization and so this is what we found...
So we had a large study based on the EVATRISP collaboration, which is a collaboration of 28 medical centers across Europe and Israel, academic centers that contribute data on patients with EVT towards a shared database. And we looked specifically at that database to see if we can find predictors for failed thrombectomy. Failed thrombectomy is basically when you perform a thrombectomy on a stroke patient, you remove the clot, and still the patient doesn’t do well, despite the fact that you have achieved complete recanalization and so this is what we found. We found predictors of that condition and we composed a scale called the FRET scale which is easy to use, basically it has some variables in it which are easily obtainable on admission, and from the FRET scale you can predict with a high likelihood, with an area under the curve of larger than 0.75, what is going to be the fate of this patient, will they do well after thrombectomy or not? Will they have failed thrombectomy? And patients who have failed thrombectomy, you know, are not going to do well.
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