WSC 2026 | PRIME: the first tool for predicting ischemic stroke after a cancer diagnosis
Ronda Lun, MD, MSc, FRCPC, University of Calgary, Calgary, Canada, discusses the development of the PRIME tool for predicting ischemic stroke after a cancer diagnosis. Dr Lun highlights how the tool can help identify high-risk patients who may benefit from primary prevention strategies, such as patient education, lifestyle modifications, or potential enrollment in clinical trials. This interview took place at the 18th World Stroke Congress (WSC) in Seoul, Korea.
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Transcript
So actually there are no existing prediction models for ischemic stroke in particular in cancer patients. This is the first prediction tool that we have looking at ischemic stroke after a new diagnosis of cancer. There are various prediction tools such as the Khorana score which predicts the risk for venous thromboembolism. But ours was the first one to look at ischemic stroke, which is really exciting...
So actually there are no existing prediction models for ischemic stroke in particular in cancer patients. This is the first prediction tool that we have looking at ischemic stroke after a new diagnosis of cancer. There are various prediction tools such as the Khorana score which predicts the risk for venous thromboembolism. But ours was the first one to look at ischemic stroke, which is really exciting. I think the way that it can be used is to try to identify a group of high-risk patients. And perhaps, you know, maybe that group of high-risk patients deserves more in terms of evaluation for primary prevention of stroke to begin with. So whether that’s patient education, whether that’s lifestyle things, or potentially in the future enrolling them in a primary prevention trial, that’s where I’m hoping that the PRIME score will go. But first we have to externally validate it in another population.
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