ESOC 2026 | Mechanical thrombectomy outcomes in patients with recurrent stroke
Guoyong Zeng, MD, Ganzhou People’s Hospital, Ganzhou, China, discusses findings from a cohort study based on individual patient data pooled from four prospective multicenter studies evaluating mechanical thrombectomy in patients with recurrent stroke. Dr Zeng highlights that although patients with prior stroke had poorer functional outcomes, reperfusion success and symptomatic intracranial hemorrhage rates were similar to those without previous stroke, supporting thrombectomy as a viable treatment option with appropriate patient selection and secondary prevention strategies. This interview took place at the 12th European Stroke Organisation Conference (ESOC) in Maastricht, The Netherlands.
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Transcript
This cohort study pooled individual patient data from four large prospective multi-centered studies. This was DEVT, MARVEL, RESCUE BT, and BASILAR, including a total of 3516 patients who underwent a mechanical thrombectomy for acute large vessel occlusion stroke within 24 hours. And the core findings on functional outcomes was that patients with a prior stroke history had a significantly lower rate of excellent 90-day functional outcome and the safety outcomes was the reperfusion rate was similar between the two groups...
This cohort study pooled individual patient data from four large prospective multi-centered studies. This was DEVT, MARVEL, RESCUE BT, and BASILAR, including a total of 3516 patients who underwent a mechanical thrombectomy for acute large vessel occlusion stroke within 24 hours. And the core findings on functional outcomes was that patients with a prior stroke history had a significantly lower rate of excellent 90-day functional outcome and the safety outcomes was the reperfusion rate was similar between the two groups. And the symptomatic intracranial hemorrhage rate was identical at 8.8% in both groups. And in conclusion, prior stroke is not a contraindication to a mechanical thrombectomy. The recurrent stroke patients still derive meaningful benefit from thrombectomy. This patient requires individualized selection and more intensive post-procedural secondary prevention to improve long-term outcomes. Thank you.
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