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ESOC 2026 | The ETIICA observational study: EVT for isolated cervical internal carotid artery occlusion

Christian Nolte, MD, Charité – Universitätsmedizin, Berlin, Germany,
discusses the findings of the ETIICA Observational Study, a large multi-center study that explored endovascular treatment (EVT) for isolated cervical internal carotid artery occlusion. The findings show EVT may not be beneficial for all patients due to complications and failure to recanalize, but may be beneficial for those with high stroke severity, distal occlusion, or those who receive stenting. This interview took place at the 12th European Stroke Organisation Conference (ESOC) in Maastricht, The Netherlands.

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Transcript

The ETIICA Observational Study was a multi-center study from centers all over the world. And please allow me to thank all the centers that contributed data. And it was the largest study ever, or so far, collecting nearly 1,000 patients with a neatly balanced part of about 500 patients receiving endovascular therapy and about 500 patients receiving best medical care. ETIICA showed that EVT is not good for all patients because of complications and because of failure to recanalize, but those patients with an NIHSS, so a very high stroke severity above 15 may profit from EVT...

The ETIICA Observational Study was a multi-center study from centers all over the world. And please allow me to thank all the centers that contributed data. And it was the largest study ever, or so far, collecting nearly 1,000 patients with a neatly balanced part of about 500 patients receiving endovascular therapy and about 500 patients receiving best medical care. ETIICA showed that EVT is not good for all patients because of complications and because of failure to recanalize, but those patients with an NIHSS, so a very high stroke severity above 15 may profit from EVT. Those with a more distal occlusion and those probably that receive stenting making sure that the vessel stays open and does not re-occlude. Although with stenting you have the problem of distal embolization and a slightly higher rate of intracranial bleed.

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Disclosures

Speaker honoraria from AstraZeneca, Bayer and Pfizer.