UK Stroke Forum 2025 | Evaluating anticoagulation for cancer-related stroke: insights from observational data

So this was work done with a superb PhD fellow, Dr. Bastien Roux, currently working in Paris. And what Bastien wrote an editorial on was an observational study looking at the risk of stroke in people with cancer. And to look to see whether in people who have cancer, anticoagulation is an effective treatment. Now in this observational study, about one in seven people who have cancer, anticoagulation is an effective treatment. Now in this observational study, about one in seven people who had cancer-associated stroke were prescribed anticoagulants in the United States, but this was only an observational study, and it’s only by doing randomized controlled trials that we’re really going to know whether anticoagulation is better than no anticoagulation in preventing stroke in these people, and what kind of anticoagulation is the very best. Because we do know that if you look across the use, say, of direct oral anticoagulants versus warfarin, that both of these apparently similar medicines have different effects in different people presenting with different coagulation-related diseases.

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