ACTRIMS 2021 | Can gold-based nanotechnology meet the need for neuro-reparative therapies in MS?

So it’s a brand new breakthrough in a therapeutic modality. And the real breakthrough is in being able to manufacture clean surfaced, pure, nano-sized crystals of therapeutic metals, which remain stable in aqueous suspension without the addition of any other excipients. So it’s using plasma physics and a lot of electricity and water, highly purified water, and highly pure wires of transition metals. And our first candidate is CNM-Au8, which is a aqueous suspension of pure gold nanocrystals. So when we say nano, these crystals are on the order of 10 to 16 nanometers in size, which means that they can easily enter cells. They can enter mitochondria, they can actually enter ribosomes. So they’re quite small and they’re pure. So they self-aggregate actually, atom by atom into preferred crystalline shapes, and they self-aggregate in highly purified water and they remain stable in highly purified water without the addition of any other excipients. And that really is the breakthrough. It’s never been possible before.

Again, it’s using plasma physics and what that allows for, these crystals allow for, direct interactions, electronic reactions into biological systems. They can directly receive thousands of electrons per second, or directly donate thousands of electrons per second. So this has really never been possible before. It’s a brand new therapeutic category and we’re very excited to be a part of it. I’m very excited to be a part of it.