ESOC 2023 | The CASES trial: should stents be placed during EVT in patients with carotid stenosis?

Paul Nederkoorn, MD, PhD, Amsterdam University Medical Centres, Amsterdam, Netherlands, discusses a novel non-inferiority trial called the CASES trial, which aims to investigate the effect of undertaking a stent placement immediately in patients with carotid stenosis during a thrombectomy. There are reported downsides of initially placing a stent in patients with carotid stenosis, which include a higher risk of further brain bleeds due to the necessity to introduce anti-platelets after the procedure. Previous cohort studies have demonstrated that placing a stent has similar outcomes to not doing so during a thrombectomy. However, there are practice variations where some clinicians will place a stent and others want to wait. This group have therefore obtained funding for a new trial in the Netherlands and Belgium comparing placing a stent immediately in patients with carotid stenosis or waiting until they have recovered to place a stent. This interview took place during the European Stroke Organisation Conference (ESOC) in Munich, Germany.

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