MDS 2023 | The impact of genetics on Parkinson’s disease diagnosis and treatment options

Prashanth Kukkle, PhD, Center for Parkinson’s Disease and Movement Disorders Clinic Vikram Hospitals, Bangalore, India, discusses the evolving field of genetics and its influence on Parkinson’s disease diagnosis and treatment. The focus has shifted from histopathology and pathological understanding to a genetic basis for diseases. By studying the role of genes in different presentations of the same disease, healthcare professionals are gaining insights into why certain individuals respond differently to treatments. This understanding of functional studies and pharmacogenomics is leading to the development of targeted therapies, such as those for Parkinson’s disease with specific gene mutations. Dr Kukkle emphasizes how genetics is changing the landscape of healthcare, allowing for more personalized approaches to treatment. This interview took place at the 2023 International Congress of Parkinson’s Disease and Movement Disorders in Copenhagen, Denmark.

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