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MDS 2023 | Clinical highlights in Parkinson’s disease

Angelo Antonini, MD, PhD, University of Padua, Padua, Italy, discusses the latest research on Parkinson’s disease and emphasizes the importance of understanding it as a systemic disease rather than solely a neurological condition. Prof. Antonini highlights that the pathological hallmarks of Parkinson’s disease can be detected not only in the brain but also in other parts of the body, such as the skin and gut. Recently, it has been shown that simple procedures like skin biopsies or blood tests can be used to detect these pathological aggregates, potentially enabling earlier diagnosis before significant neuron loss occurs. Additionally, Prof. Antonini emphasizes the need for early detection, comparing it to diagnosing cancer at an early stage. Other highlights are the ongoing development of biological therapies to halt disease progression and the need to implement them before substantial brain neuron loss occurs. This interview took place at the 2023 International Congress of Parkinson’s Disease and Movement Disorders in Copenhagen, Denmark.

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