EAN 2025 | The economic impact of reducing off-time and extending on-time in patients with Parkinson’s disease

We interviewed many patients from different countries and one of the objectives was really to prove that reducing off-time and extending on-time, even by one hour, has a profound impact not only on activities of daily living but also may have an economic impact. And we reviewed patients from the G7 countries, so the largest countries in the world in terms of population and GDP. And even in those countries where medical care is generally considered to be efficient, experiencing off-time may have an impact on patient independence, may lead more often to hospital admissions, into nursing homes, or sudden falls, or being forced to quit the job. This is very important to establish, because in each country, the price of a drug is negotiated, often it is asked, what is this drug doing? How much can we quantify the impact of a single medication. By providing data from a large cohort of patients all over the world, even in relatively rich countries, I think we’ve proven that extending the on-time by even one hour has a profound economical impact and may reduce not only disability but improve the functionality and the ability of people to continue working.

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