Educational content on VJNeurology is intended for healthcare professionals only. By visiting this website and accessing this information you confirm that you are a healthcare professional.

Share this video  

AES 2022 | The TSC Alliance’s Natural History Database

Gabrielle Rushing, PhD, TSC Alliance, talks on the tuberous sclerosis complex (TSC) Natural History Database and biosample repository, established by the TSC Alliance in 2006 to identify potential participants for clinical studies. Over the years, the dataset has grown to become a rich resource for TSC researchers, with more than 2000 people enrolled in the project. Investigators can request to utilize the data and connected biosamples in their studies free of charge. The recently launched efforts to expand the genetic information available in the database will see as many as 500 participants receive whole genome sequencing. To date, 16 articles have been published using data from the TSC Natural History Database, contributing to our understanding of the disease. Future work using the genomic data will likely improve our understanding of novel genetic modifiers and genotype-phenotype correlations. This interview took place at the American Epilepsy Society (AES) Annual Meeting 2022 in Nashville, TN.

These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.