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IEC 2025 | The need for further research to understand the effects of climate change on epilepsy

Medine Gulcebi Idriz Oglu, MD, Marmara University, Istanbul, Turkey, comments on the significant research gap in understanding the effects of climate change on individuals with epilepsy. She highlights the need to investigate vulnerability and responses to anti-seizure medications, including how temperature fluctuations impact the pharmacological characteristics and adverse effects of medications. This interview took place at the 36th International Epilepsy Congress (IEC) in Lisbon, Portugal.

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Transcript

There is a huge research gap for climate change effects on people with epilepsy. When we look at the literature, we see scarce information, especially for people with epilepsy, for the effects of adverse weather events on these people with epilepsy. For example, vulnerability. As I said, the vulnerability of each of the patients to climate change effects is a major problem. Firstly, we should explore, in order to explore this question, we need to do research on the vulnerability of the people to climate change effects...

There is a huge research gap for climate change effects on people with epilepsy. When we look at the literature, we see scarce information, especially for people with epilepsy, for the effects of adverse weather events on these people with epilepsy. For example, vulnerability. As I said, the vulnerability of each of the patients to climate change effects is a major problem. Firstly, we should explore, in order to explore this question, we need to do research on the vulnerability of the people to climate change effects. Or about medications. So we know, again, we have little information, evidence-based information for anti-seizure medications. How the temperature fluctuations affect the pharmacological characteristics of each of the anti-seizure medications is another important research area. Or not only the pharmacological characteristics, but also drug response may change. So we need to understand how drug response changes during adverse weather events in people with epilepsy. This is another important area. And also the adverse effects of anti-seizure medications is another important research area. So for disease-based and for medication-based research, the gap is huge and we need to explore these, I think, in the near future.

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