ESOC 2023 | Predicting likelihood of delayed reperfusion to guide adjunctive therapy use after EVT

Researchers in the field of ischemic stroke are investigating ways to improve outcomes after endovascular thrombectomy (EVT) using adjunctive therapies. These additional reperfusion efforts, such as intra-arterial thrombolysis, are showing promise as a way to improve tissue perfusion at the microvascular level, but they are not without risks. Adnan Mujanovic, MD, PhD Candidate from Inselspital, Bern University Hospital, discusses the challenges and potential risks associated with adjunctive procedures for incomplete reperfusion and the importance of developing models to predict who is most likely to benefit. For instance, additional thrombolytics can increase the risk of hemorrhage, while secondary distal mechanical thrombectomy may lead to vessel rupture. To address this issue, Dr Mujanovic and his team developed a clinical prediction model to assist healthcare professionals in selecting patients who are most likely to benefit from additional reperfusion efforts. This model helps identify patients who would not benefit from such interventions, sparing them from potential risks. This interview took place during the European Stroke Organisation Conference (ESOC) in Munich, Germany.

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