Individuals with nonvalvular atrial fibrillation (AF) are at increased risk of cognitive impairment and dementia. Alvi Rahman, PhD candidate, McGill University, Montreal, Canada delves into the mechanisms governing the relationship between oral anticoagulant (OAC) use in patients with AF and the consequential reduction in dementia risk. AF can lead to overt clinical stroke, which is associated with vascular dementia. It also gives rise to silent manifestations such as silent strokes and microembolisms, which are often undetected as risk factors for vascular dementia. In this way, OACs may reduce the risk of dementia by mitigating the downstream effects of AF. This interview took place at the World Stroke Congress (WSC) 2023 in Toronto, Canada.
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