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AAN 2021 | Identifying cognitive phenotypes in multiple sclerosis

Ermelinda De Meo, MD, University Vita-Salute San Raffaele, Milan, Italy, discusses a study identifying cognitive phenotypes in multiple sclerosis (MS) presented at the American Academy of Neurology (AAN) 2021 Annual Meeting. Cognitive impairment is a relevant feature of MS patients, and to date, there is no specific classification for these symptoms. Dr De Meo explains that the study’s objective was to identify cognitive phenotypes to be used along with the Expanded Disability Status Scale (EDSS) to enable the classification of patients and the use of a tailored rehabilitative treatment. The study was able to recognize five cognitive phenotypes advancing the research on neuroanatomic substrates of MS.