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ESOC 2023 | Impact of intravenous thrombolysis on delayed reperfusion in SWIFT-DIRECT

Adnan Mujanovic, MD, PhD Candidate from Inselspital, Bern University Hospital, presents a subgroup analysis from the SWIFT-DIRECT trial, focusing on the interaction between intravenous thrombolysis (IVT) and delayed reperfusion after endovascular thrombectomy (EVT). While there have been several recent trials exploring the efficacy of additional IVT in thrombectomy procedures, the specific interaction with delayed reperfusion and persistent perfusion deficit has been a subject of interest. Based on the data obtained, no direct correlation was observed between the use of IVT and delayed reperfusion rates. However, other factors were found to be associated with delayed reperfusion, such as reperfusion score on the TICI scale, collateral scores, and the presence of atrial fibrillation. Additionally, the time between final angiography and 24-hour follow-up imaging was found to influence the likelihood of delayed reperfusion. This interview took place during the European Stroke Organisation Conference (ESOC) in Munich, Germany.

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