ACTRIMS 2026 | Depression in people with MS: prevalence and implications for disease outcomes
David Freedman, MD, University of Toronto, Toronto, Canada, discusses the prevalence of depression in individuals with multiple sclerosis (MS), noting that it occurs in up to 50% of patients. Dr Freedman highlights that depression can have a significant impact on quality of life, employment outcomes, and potentially even mortality in people with MS. This interview is part of our coverage of the 11th Annual Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) Forum, held in San Diego, CA.
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Transcript
So although often under-recognized and at times under-treated, depression occurs in about up to 50% of individuals with multiple sclerosis, and some studies cite approximately 25 to 30% at any given time point will have depression. And in terms of its impact on other outcomes, we know that depression can adversely impact the quality of life, employment outcomes, and some studies have even shown a potential influence on mortality in people with multiple sclerosis...
So although often under-recognized and at times under-treated, depression occurs in about up to 50% of individuals with multiple sclerosis, and some studies cite approximately 25 to 30% at any given time point will have depression. And in terms of its impact on other outcomes, we know that depression can adversely impact the quality of life, employment outcomes, and some studies have even shown a potential influence on mortality in people with multiple sclerosis.
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