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SLEEP 2026 | Does long-term hypnotic use increase the risk of cognitive impairment?

Bhanu Prakash Kolla, MD, MRCPsych, Mayo Clinic, Rochester, MN, discusses findings from a large retrospective cohort study examining the relationship between hypnotic use and cognitive impairment. He explains how adjusting for insomnia severity, genetic risk factors, and prescribing propensity challenged the long-held assumption that long-term use of certain hypnotics increases the risk of mild cognitive impairment or dementia. This interview took place at the 40th annual meeting of the Associated Professional Sleep Societies (APSS) in Baltimore, MD.

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