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Michael Heneka, MD, University of Bonn, Bonn, Germany, discusses inflammation in Alzheimer’s disease (AD). Recently, there has been a lot of evidence supporting the role of inflammation in the pathogenesis of AD. However, there are still a lot of questions left unanswered, for instance, the optimal time for intervention. This interview took place during the Virtual World Congress on Controversies in Neurology (CONy) 2020.