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CONy 2024 | An overview of functional cognitive disorder

Narinder Kapur, PhD, Dip Psych, University College London, London, UK, introduces functional cognitive disorder (FCD), a relatively common but under-recognized cause of cognitive symptoms. This term refers to patients experiencing cognitive symptoms that are associated with distress or disability but that don’t have a clear medical cause. These symptoms, often memory-related, are caused by functional alterations and don’t align with known psychiatric conditions or neurological disorders. Symptoms often have a sudden onset and show internal inconsistency. Patients might exhibit comorbid conditions such as fatigue, sleep issues, pain, or anxiety. They could also show attentional problems, tending to hyper-focus on their symptoms, fearing conditions like dementia. Notably, a discrepancy between subjective reports and objective measures is common in FCD, with individuals often performing well on neuropsychological tests, unlike those with organic conditions. These features help distinguish functional cognitive disorders from other conditions. This interview took place at the 18th Annual Congress on Controversies in Neurology (CONy 2024) in London, UK.

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Transcript

Functional cognitive disorders, there’s not a standard sort of cast iron definition of them, but they’re usually defined as patients complaining of cognitive symptoms, they’re causing them some distress, but they’re not readily explained by any medical or neurological condition. And there’s usually some features of them, such as inconsistency, which seems to set them apart from neurological disorders...

Functional cognitive disorders, there’s not a standard sort of cast iron definition of them, but they’re usually defined as patients complaining of cognitive symptoms, they’re causing them some distress, but they’re not readily explained by any medical or neurological condition. And there’s usually some features of them, such as inconsistency, which seems to set them apart from neurological disorders. So generally, as I said, used to consider those patients who are complaining often of memory symptoms, but it could be other cognitive symptoms as well, quite disabling for them, but there’s no obvious medical cause for them and they can’t be explained by a psychiatric condition or things like that and there are features which seem to set them apart from neurological disorders.

The functional cognitive disorders, they can have a number of features. First of all, there may be what’s called comorbid conditions. So there may be things like fatigue problems, sleep problems, pain, headache, things like that, and obviously anxiety and mood. There may have been some stressful events etc. So one’s looking at the presence of comorbid features. Then there may be what’s called attentional problems, they’re really paying lots of attention, hypervigilant to their symptoms. And they may have what’s called health anxiety as well, they may have beliefs that they may be getting dementia and things like that. So they may have strong beliefs that they’ve got a particular type of illness. So, those are some of the clinical features. They will often describe their symptoms in great detail. That’s often indicated as one of the features. And there may be a sudden onset and that may set them apart. So, those are some of the clinical features and, in terms of neuropsychological functioning, I think one of the characteristics is that they’re often performing well on neuropsychological tests, and that sets them apart from patients with organic conditions. They may have 1 or 2 impairments, but they’re generally fairly mild, and they may be on speed of processing tests and things like that. So those are the sorts of things which tends to set them apart.

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