ESOC 2023 | The contribution of stroke to neurodegenerative disease

Kyle Kern, MD, National Institute of Neurological Disorders and Stroke (NINDS), Bethesda, MD, discusses the relative contribution of stroke to neurodegenerative disease. The risk of dementia is increased with stoke, in both vascular and Alzheimer’s disease dementia. Research is currently being undertaken to assess how the effects of a stroke may lead to neurodegenerative processes. Indeed, questions remain as to whether stroke may act as the trigger or simply unmask neurodegenerative processes that were already ongoing. There is some evidence that vascular risk factors leading to a stroke also increase the risk of neurodegenerative disease. Identification of biomarkers that connect vascular risk factors to neurodegenerative disease will help to select patients at a greater risk of cognitive decline and therefore more likely to benefit from intervention. This interview took place during the European Stroke Organisation Conference (ESOC) in Munich, Germany.

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