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Orexin agonists in narcolepsy: current evidence and future directions
In this episode of the VJNeurology Podcast, we explore the rapidly evolving landscape of orexin agonists for the treatment of narcolepsy. Following the recent FDA approval of oveporexton, as well as new clinical trial data on alixorexton and E2086, experts discuss the latest evidence, emerging developments, and what these advances could mean for the future of narcolepsy treatment.
Featuring Nancy Foldvary-Schaefer, DO, Cleveland Clinic, Cleveland, OH, Emmanuel Mignot, MD, PhD, Stanford University School of Medicine, Palo Alto, CA, Lucie Barateau, MD, PhD, Gui-de-Chauliac Hospital, CHU Montpellier, Montpellier, France, and Bruce Corser, MD, FAASM, Intrepid Research, Cincinnati, OH.
Date: 4th September 2026
