EAN 2026 | Beyond seizure frequency: assessing treatment response in epilepsy
Manuel Toledo, MD, PhD, VHIR Vall d’Hebron Institut de Recerca, Barcelona, Spain, discusses the importance of assessing treatment response in epilepsy beyond seizure frequency alone. He highlights the value of caregiver input, seizure diaries, and emerging wearable technologies that could provide objective measures of seizure frequency and severity. This interview took place at the 12th Congress of the European Academy of Neurology (EAN) in Geneva, Switzerland.
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Transcript
I would say that it is important to make a good clinical anamnesis to differentiate whether the patient has a good response or not to different anti-seizure medications. And it’s not only a dichotomic decision whether the patients respond or do not respond. We must explore the different outcomes of the patients, taking into account witnesses like caregivers or some of the devices and tools like cell phones or seizure diaries and so on...
I would say that it is important to make a good clinical anamnesis to differentiate whether the patient has a good response or not to different anti-seizure medications. And it’s not only a dichotomic decision whether the patients respond or do not respond. We must explore the different outcomes of the patients, taking into account witnesses like caregivers or some of the devices and tools like cell phones or seizure diaries and so on. There’s a lot of different devices coming up to the market. Many of them, they still depend pretty much on the patients or relative clicking on whether they had seizures or not. However, there’s a lot of different devices coming up that they can automatically record where the patient had a seizure or not. And that will be radically different from what we have today because it’s not just the subjective experience of the patients. It’s an objective way to measure the number or even the severity of seizures. I know, like wristbands, the devices or rings that they are able to control not only the seizure frequency or severity, but other aspects of the disease like sleep disorders or cognitive function or exercise, which is really important for patients with epilepsy.
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