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AAN 2026 | Unmet needs in the management of pediatric migraine

Sara Pavitt, MD, University of Texas, Austin, TX, comments on the unmet needs in the management of pediatric migraine. Dr Pavitt highlights the need for more treatment trials and a better understanding of how to help these individuals integrate into daily life. This interview took place at the 78th American Academy of Neurology (AAN) Annual Meeting in Chicago, IL.

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Transcript

There are a lot of unmet needs when it comes to pediatric patients who have migraines. I think one of the biggest areas is having more treatment trials and understanding what is the best way to approach treatment with these patients. We’ve had a handful of really well-run randomized controlled trials, but really right now we only have two medications that are FDA approved for prevention for pediatric patients who have migraines...

There are a lot of unmet needs when it comes to pediatric patients who have migraines. I think one of the biggest areas is having more treatment trials and understanding what is the best way to approach treatment with these patients. We’ve had a handful of really well-run randomized controlled trials, but really right now we only have two medications that are FDA approved for prevention for pediatric patients who have migraines. And so one big area is being able to fund and run trials that really give us some more evidence base around the practice of pediatric patients with migraines. I think the other really big unmet need is really figuring out how do our pediatric patients, how can we optimize our pediatric patients’ ability to function within their own environment? We know that migraines can lead to significant disability. It’s the second leading cause of disability in patients 16 to 49. And that involves school, social life, family life. How are kids thinking about going to college or starting their first job? And so I would love, I think there’s a big need to understand how do we help our patients integrate into daily life? How do we advocate for them in school? And really help to target the potential disability and functional limitations that can come with this disorder.

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