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SLEEP 2026 | Precision endotype-guided treatment of OSA

Danny Eckert, PhD, Flinders University, Adelaide, Australia, discusses the expanding landscape of precision medicine for obstructive sleep apnea (OSA). He reviews emerging therapies targeting distinct pathophysiological endotypes, including oral appliances, hypoglossal nerve stimulation, pharmacological approaches, and combination therapies, and explains how endotype-guided treatment selection may improve patient outcomes and reduce disease burden. This interview took place at the 40th annual meeting of the Associated Professional Sleep Societies (APSS) in Baltimore, MD.

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