AAN 2024 | The mechanism of action of CNM-Au8 and its potential in various neurodegenerative diseases

Michael Barnett, MBBS, FRACP, PhD, Royal Prince Alfred Hospital Sydney, Sydney, Australia, discusses the mechanism of action of the novel therapeutic CNM-Au8. This therapy consists of gold nanocrystals that penetrate neurons and glial cells to promote cellular energetics, and potentially recover cells susceptible to degeneration. Theoretically, it has applications in various neurodegenerative diseases including Alzheimer’s disease (AD), Parkinson’s disease (PD), and amyotrophic lateral sclerosis (ALS), as well as multiple sclerosis (MS). This interview took place at the American Academy of Neurology (AAN) Annual Meeting 2024 in Denver, CO.

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