The headache field has seen significant advances in the understanding and care of patients. Nevertheless, some areas within the field require further research in order to improve headache care. Oved Daniel, MD, Ramat Aviv Medical Center, Tel-Aviv, Israel, discusses the importance of understanding the pathophysiological mechanisms of post-traumatic headache. Another relevant topic that requires more data is the safety of low-estrogen pills for menstruation-related migraine. This interview was conducted during the virtual 2021 World Congress on Controversies in Neurology (CONy).