Yohannes Woldeamanuel, MD, Stanford University, Stanford, CA, describes the future of proteomic research in the context of migraine and personalized medicine. Compared to other -omics, metabolomics is the closest to the phenotype; however, metabolomics requires a lot of filtering to remove noise prior to investigating the biological phenomena. In comparison, proteomics can inform us of proteins specific to that patient’s population. Similarly, hundreds of genes have been linked to migraine, making it very challenging to use genetic data to classify patients. This interview took place at the American Headache Society 2023 meeting in Austin, TX.
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