ESOC 2024 | REMOTE-CAT: remote ischemic perconditioning shows benefit in acute ischemic stroke

Francisco Purroy, PhD, Institut de Recerca Biomèdica de Lleida, Lleida, Spain, shares the results of the REMOTE-CAT project, which investigated the impact of remote ischemic perconditioning (RIPerC) as a novel neuroprotective strategy for patients with acute ischemic stroke. RIPerC employs brief episodes of transient limb ischemia in an effort to upregulate endogenous defense systems to achieve ischemic tolerance and thus, mitigate cerebral damage. In REMOTE-CAT, patients from four centers in Catalonia were treated with five cycles of RIPerC or sham stimulation in the ambulance. At 90 days post-stroke, mRS 0-2 was achieved by 64.9% in the RIPerC arm, compared to 47% in the sham arm. The improvement was strongest in those with lower NIHSS scores and those without large vessel occlusion. This interview took place at the 10th European Stroke Organisation Conference (ESOC) 2024 in Basel, Switzerland.

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