Ray Chaudhuri, MD, DSc, FRCP, FEAN, King’s College London, London, UK, discusses the challenges faced in understanding and researching non-motor symptoms in Parkinson’s disease. There is a lack of understanding and research in many areas, making it difficult to distinguish between symptoms related to Parkinson’s disease and those observed in the general population. Additionally, overlap occurs between different subtypes of non-motor symptoms in advanced stages of the disease. The natural history of these symptoms and their long-term outcomes remain unclear. Treatment for non-motor symptoms is still suboptimal, lacking evidence-based approaches for various symptoms. Prof. Chaudhuri emphasizes the importance of improved clinical trials, quality-of-life assessments, and the use of aids such as validated questionnaires and dashboards. This interview took place at the 2023 International Congress of Parkinson’s Disease and Movement Disorders in Copenhagen, Denmark.
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